The Department of Medical and Molecular Genetics at Indiana University School of Medicine is seeking applicants at the Postdoctoral Fellow level. The Ware lab investigates the genetic and developmental basis of pediatric heart disease. We analyze genetic variation in samples from patients with congenital heart defects and utilize mouse, Xenopus and cell-based models to assess these variants. Our lab also uses these models to study genes previously linked to congenital cardiac defects, with a particular focus on left-right patterning genes.

IU School of Medicine is committed to being a welcoming campus community and we seek candidates whose research, teaching, and community engagement efforts contribute to robust learning and working environments for all students, staff, and faculty. We invite individuals who will join us in our mission to improve health equity and well-being for all throughout the state of Indiana.

Applications will be received until the position is filled.

Stephanie Ware, MD, Phd (https://medicine.iu.edu/faculty/22816/ware-stephanie) is the Chair of the Department of Medical and Molecular Genetics as well as the program leader of the Cardiovascular Genetics Program within the Wells Center of Pediatric Research. Her long-term research goal is to identify causes of congenital heart defects.

The successful candidates must have a Ph.D. degree with a strong research background in genetics and/or developmental biology. Candidates should have experience with mouse or Xenopus models and molecular biology techniques. Experience collecting/processing mouse embryos, particularly at early stages of development, is highly desirable. Experience with cell culture, immunofluorescence or in situ hybridization would be considered a plus.

Questions related to this job posting can be directed to Maria Padua: mpadua@iu.edu

The candidates must be self-motivated, well-organized and comfortable mentoring graduate students in basic techniques. A successful candidate must have experience collecting/analyzing/interpreting data and will be expected to participate in manuscript preparation and grant development. It is highly desirable for the holders of this position to develop research projects with strong potential for long-term NIH funding, and to have demonstrated the ability to collaborate with others.

Example publications · Congenital heart defects caused by FOXJ1 https://pubmed.ncbi.nlm.nih.gov/37158461/

· Loss of Zic3 impairs planar cell polarity leading to abnormal left-right signaling, heart defects and neural tube defects https://pubmed.ncbi.nlm.nih.gov/34274973/